ACP Journal Club. Adding procalcitonin-guided therapy to standard care did not reduce mortality in critically ill patients.


Main results Adding PCT-guided therapy to standard care did not reduce 28-day mortality or proportion of patients with renal dysfunction at discharge or death (Table). Patients in the PCT-guided group had longer stays in the ICU (median 6 vs 5 d, P = 0.004), and while in the ICU, more days on mechanical ventilation (66% vs 61%; difference 4.9%, 95% CI 3.0… (More)
DOI: 10.7326/0003-4819-156-4-201202210-02006


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