ACOG Practice Bulletin No. 196: Thromboembolism in Pregnancy.

@article{Birsner2018ACOGPB,
  title={ACOG Practice Bulletin No. 196: Thromboembolism in Pregnancy.},
  author={Meredith L. Birsner and Anjali J. Kaimal},
  journal={Obstetrics \& Gynecology},
  year={2018}
}
Women who are pregnant or in the postpartum period have a fourfold to fivefold increased risk of thromboembolism compared with nonpregnant women (). Approximately 80% of thromboembolic events in pregnancy are venous (), with a prevalence of 0.5-2.0 per 1,000 pregnant women (). Venous thromboembolism (VTE) is one of the leading causes of maternal mortality in the United States, accounting for 9.3% of all maternal deaths ().The prevalence and severity of this condition during pregnancy and the… 
132 Citations

Risk factors for and clinical management of venous thromboembolism during pregnancy.

TLDR
Women with a personal or strong family history of VTE, as well as documented thrombophilia, represent a unique group in whom antepartum and/or postpartum prophylaxis can be considered.

ACOG Practice Bulletin No. 197: Inherited Thrombophilias in Pregnancy.

TLDR
This Practice Bulletin has been revised to provide additional information on recommendations for candidates for thrombophilia evaluation, updated consensus guidelines regarding the need for prophylaxis in women with an inherited thromBophilia during pregnancy and the postpartum period, and discussion of new published consensus guidelines from the Society for Obstetric Anesthesia and Perinatology.

Prevention of Venous Thromboembolism during Pregnancy and the Puerperium with a Special Focus on Women with Hereditary Thrombophilia or Prior VTE-Position Paper of the Working Group in Women's Health of the Society of Thrombosis and Haemostasis (GTH).

TLDR
This document focuses on women with hereditary thrombophilia, prior VTE and the use of anticoagulants that can safely be applied during pregnancy and the lactation period.

Venous thromboembolism prophylaxis for women at risk during pregnancy and the early postnatal period.

TLDR
The effects of thromboprophylaxis during pregnancy and the early postnatal period on the risk of venous thromboembolic disease and adverse effects in women at increased risk of VTE was assessed.

United Kingdom recommendations for obstetric venous thromboembolism prophylaxis: Evidence and rationale.

TLDR
The pathophysiology of VTE in pregnancy, evidence behind the risk factors for VTE and the use of thromboprophylactic agents are addressed.

Venous Thromboembolism Risk Score and Pregnancy

TLDR
The existing VTE risk scores during the antenatal and postnatal period are described and the important message beyond the score used is that all women should undergo VTErisk factor assessment.
...

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ACOG Practice Bulletin No. 197: Inherited Thrombophilias in Pregnancy.

TLDR
This Practice Bulletin has been revised to provide additional information on recommendations for candidates for thrombophilia evaluation, updated consensus guidelines regarding the need for prophylaxis in women with an inherited thromBophilia during pregnancy and the postpartum period, and discussion of new published consensus guidelines from the Society for Obstetric Anesthesia and Perinatology.

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TLDR
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The roles of acquired and inherited thrombophilia in furthering the hypercoagulable state of pregnancy are described, the potential consequences of using anticoagulants during pregnancy are identified, and the treatment options are summarized.
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