ACG Clinical Guideline: Primary Sclerosing Cholangitis
@article{Lindor2015ACGCG, title={ACG Clinical Guideline: Primary Sclerosing Cholangitis}, author={Keith D. Lindor and Kris V. Kowdley and M Edwyn Harrison}, journal={The American Journal of Gastroenterology}, year={2015}, volume={110}, pages={646-659} }
Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and may require liver transplantation. The cause is unknown, although it is commonly associated with colitis. There is no approved or proven therapy, although ursodeoxycholic acid is used by many on an empiric basis. Complications including portal hypertension, fat-soluble vitamin deficiency, metabolic bone diseases, and development of cancers of the bile duct or colon can occur.
329 Citations
Primary Sclerosing Cholangitis: What the Gastroenterologist and Hepatologist Needs to Know.
- MedicineClinics in liver disease
- 2017
Primary Sclerosing Cholangitis
- MedicineThe New England journal of medicine
- 2016
Management should be treatment of symptoms and complications of cholestasis, as well as attempts at treating the underlying disease process, and efforts should be made to recognize and treat or prevent the known complications of primary sclerosing cholangitis.
Primary sclerosing cholangitis: diagnostic and management challenges
- MedicineClinical and experimental gastroenterology
- 2017
The diagnostic and management challenges of PSC are addressed, with a succinct analysis of existing therapies, their limitations, and a glimpse into the future of the management of this multifaceted pathologic entity.
Primary Sclerosing Cholangitis: Therapeutic Options and Surveillance Management
- MedicineClinical medicine insights. Gastroenterology
- 2016
An overview of primary sclerosing cholangitis is provided with further focus on current therapeutic options and guidance on surveillance management.
Endoscopic Evaluation and Management of Primary Sclerosing Cholangitis
- Medicine
- 2017
The central role of endoscopy in the initial diagnosis of PSC, endoscopic evaluation and endotherapy for dominant strictures, endoscope evaluation for development of CCA, and endoscopic evaluated and management of recurrent PSC after liver transplantation are reviewed.
Primary sclerosing cholangitis and inflammatory bowel disease: Intestine-liver interrelation.
- MedicineGastroenterologia y hepatologia
- 2019
Biliary endoscopy in the management of primary sclerosing cholangitis and its complications
- MedicineLiver research
- 2019
Primary sclerosing cholangitis and inflammatory bowel disease: Intestine–liver interrelation
- MedicineGastroenterología y Hepatología (English Edition)
- 2019
Primary Biliary Cholangitis and Primary Sclerosing Cholangitis.
- MedicineThe American journal of gastroenterology
- 2019
This review will address the general clinical features of primary biliary cholangitis and primary sclerosing cholangsitis, analyze their commonalities and differences, and provide a state-of-the art overview of the currently available therapeutics.
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Background: Results from a pilot investigation with tacrolimus for primary sclerosing cholangitis (PSC) demonstrated biochemical improvement without excessive drug toxicity. To date, no confirmatory…