ACEII, a novel transcriptional activator involved in regulation of cellulase and xylanase genes of Trichoderma reesei.

@article{Aro2001ACEIIAN,
  title={ACEII, a novel transcriptional activator involved in regulation of cellulase and xylanase genes of Trichoderma reesei.},
  author={Nina Aro and Anu Saloheimo and Marja Ilm{\'e}n and Meria E. Penttil{\"a}},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 26},
  pages={24309-14}
}
A novel yeast-based method to isolate transcriptional activators was applied to clone regulators binding to the cellulase promoter cbh1 of the filamentous fungus Trichoderma reesei (Hypocrea jecorina). This led to the isolation of the cellulase activator ace2 encoding for a protein belonging to the class of zinc binuclear cluster proteins found exclusively in fungi. The DNA-binding domain of ACEII was expressed as a glutathione S-transferase fusion protein in Escherichia coli, and ACEII was… CONTINUE READING
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Cellulase Activator ACEII of T. reesei 24314 by gest on N ovem er 17

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