ACE2 Cell Biology, Regulation, and Physiological Functions

@article{Turner2015ACE2CB,
  title={ACE2 Cell Biology, Regulation, and Physiological Functions},
  author={A. Turner},
  journal={The Protective Arm of the Renin Angiotensin System (RAS)},
  year={2015},
  pages={185 - 189}
}
  • A. Turner
  • Published 2015
  • Biology
  • The Protective Arm of the Renin Angiotensin System (RAS)
  • Abstract Angiotensin-converting enzyme 2 (ACE2), discovered as a homologue of ACE, acts as its physiological counterbalance providing homeostatic regulation of circulating angiotensin II (Ang II) levels. ACE2 is a zinc metalloenzyme and carboxypeptidase located as an ectoenzyme on the surface of endothelial and other cells. While its primary substrate appears to be Ang II, it can hydrolyze a number of other physiological substrates. Additionally, ACE2 functions in other noncatalytic… CONTINUE READING

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