ACE polymorphisms.

  title={ACE polymorphisms.},
  author={Fakhredin A. Sayed-Tabatabaei and Ben A. Oostra and Adrian M. Isaacs and Cornelia M van Duijn and Jacqueline C. M. Witteman},
  journal={Circulation research},
  volume={98 9},
Angiotensin converting enzyme (ACE) plays an essential role in two physiological systems, one leading to the production of angiotensin II and the other to the degradation of bradykinin. The wide distribution and multifunctional properties of these peptides suggest that ACE could be involved in various pathophysiological conditions. The discovery that ACE levels are under genetic control ushered in a new era of investigation; most studies focused on an insertion/deletion (I/D) polymorphism in… CONTINUE READING
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