ACE inhibitors are linked to increased lung cancer risk, study finds

@article{Kmietowicz2018ACEIA,
  title={ACE inhibitors are linked to increased lung cancer risk, study finds},
  author={Zosia Kmietowicz},
  journal={British Medical Journal},
  year={2018},
  volume={363}
}
  • Z. Kmietowicz
  • Published 24 October 2018
  • Medicine
  • British Medical Journal
Angiotensin converting enzyme inhibitors (ACEIs) are associated with a higher risk of lung cancer than angiotensin receptor blockers (ARBs), especially if used for more than five years, a study in The BMJ has found.1 Although the risk to individual patients is modest, the absolute numbers of patients at risk for lung cancer is potentially large because ACEIs are widely prescribed, said the researchers. Evidence suggests that ACEIs increase the risk of lung cancer through the build-up of… 

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References

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Angiotensin converting enzyme inhibitors and lung cancer

TLDR
Any extra risk must be balanced against the mortality benefits of ACEI use to decide whether to continue using ACEI in patients with a history of heart attack or stroke.

Angiotensin converting enzyme inhibitors and risk of lung cancer: population based cohort study

TLDR
In this population based cohort study, the use of ACEIs was associated with an increased risk of lung cancer, and the association was particularly elevated among people using ACEIs for more than five years.