ACE inhibitors and statins acutely improve endothelial dysfunction of human coronary arterioles.

@article{Tiefenbacher2004ACEIA,
  title={ACE inhibitors and statins acutely improve endothelial dysfunction of human coronary arterioles.},
  author={Christiane Pia Tiefenbacher and Stefanie Friedrich and Tina Bleeke and Christian Friedrich Vahl and Xiaobo Chen and Feraydoon Niroomand},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2004},
  volume={286 4},
  pages={H1425-32}
}
Long-term treatment with angiotensin-converting enzyme (ACE) inhibitors as well as angiotensin II type 1 (AT(1)) receptor antagonists and statins reduces cardiovascular mortality in patients with coronary artery disease as well as chronic heart failure. Little is known about the acute effects of these compounds on vascular reactivity of coronary resistance vessels. Coronary arterioles were obtained from patients undergoing coronary bypass operation (atherosclerosis group) or valve replacement… CONTINUE READING