ACE inhibition reduces left ventricular mass independent of pressure without affecting coronary flow and flow reserve in spontaneously hypertensive rats.

@article{Kaneko1997ACEIR,
  title={ACE inhibition reduces left ventricular mass independent of pressure without affecting coronary flow and flow reserve in spontaneously hypertensive rats.},
  author={Kotaro Kaneko and Dinko Su{\vs}i{\'c} and Eduardo Nunez and Edward David Frohlich},
  journal={The American journal of the medical sciences},
  year={1997},
  volume={314 1},
  pages={21-7}
}
Systemic and regional (including coronary) hemodynamics were studied in spontaneously hypertensive and normotensive Wistar Kyoto rats after 3 weeks of treatment with one of the three doses of the angiotensin converting enzyme inhibitor, ramipril. The effects of respective treatments on cardiovascular mass and systemic, coronary, and regional hemodynamics (at rest, during maximal treadmill exercise, and during dipyridamole infusion) then were evaluated in conscious rats using radiomicrosphere… CONTINUE READING

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