ACE Inhibition with moexipril: a review of potential effects beyond blood pressure control.

@article{Pines2003ACEIW,
  title={ACE Inhibition with moexipril: a review of potential effects beyond blood pressure control.},
  author={Amos Pines and Enrique Z Fisman},
  journal={American journal of cardiovascular drugs : drugs, devices, and other interventions},
  year={2003},
  volume={3 5},
  pages={
          351-60
        }
}
ACE inhibitors induce metabolic changes and exert cardioprotective and vasoprotective properties, some of which cannot be attributed to their antihypertensive effect per se. Moexipril is an ACE inhibitor with a lipophilicity in the same range as quinapril, benazepril or ramipril, and so can readily penetrate lipid membranes and thus target tissue ACE in addition to plasma ACE. Evidence from animal studies shows similar and significant (p < 0.05) reductions in tissue ACE activity for moexipril… CONTINUE READING

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