ACE-DD genotype is associated with the occurrence of acute coronary syndrome in postmenopausal women.

@article{Mthot2005ACEDDGI,
  title={ACE-DD genotype is associated with the occurrence of acute coronary syndrome in postmenopausal women.},
  author={Julie M{\'e}thot and Bettina A Hamelin and Peter M Bogaty and Marie Arsenault and Sylvain Plante and Paul Poirier},
  journal={International journal of cardiology},
  year={2005},
  volume={105 3},
  pages={308-14}
}
The insertion/deletion (I/D) polymorphism of the angiotensin converting enzyme (ACE), the A1166C polymorphism in the angiotensin type 1 receptor (AT1R), and the M235T polymorphism of the angiotensinogen gene are associated with cardiovascular disease mostly in men. Few data are available on the effects of these genetic variations in postmenopausal women according to hormone replacement therapy (HRT) use. In this case-control study, we determine the frequency of mutant alleles in the ACE I/D… CONTINUE READING
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