ABP1 Mediates Auxin Inhibition of Clathrin-Dependent Endocytosis in Arabidopsis

  title={ABP1 Mediates Auxin Inhibition of Clathrin-Dependent Endocytosis in Arabidopsis},
  author={St{\'e}phanie Robert and J{\"u}rgen Kleine-Vehn and Elke Barbez and Michael Sauer and Tomasz Paciorek and Pawel Baster and Steffen Vanneste and Jing Zhang and Sibu Simon and Milada {\vC}ovanov{\'a} and Kenichiro Hayashi and Pankaj Dhonukshe and Zhenbiao Yang and Sebastian Y Bednarek and Alan M. Jones and C. Luschnig and Fernando Aniento and Eva Za{\vz}{\'i}malov{\'a} and Jiř{\'i} Friml},
Spatial distribution of the plant hormone auxin regulates multiple aspects of plant development. These self-regulating auxin gradients are established by the action of PIN auxin transporters, whose activity is regulated by their constitutive cycling between the plasma membrane and endosomes. Here, we show that auxin signaling by the auxin receptor AUXIN-BINDING PROTEIN 1 (ABP1) inhibits the clathrin-mediated internalization of PIN proteins. ABP1 acts as a positive factor in clathrin recruitment… CONTINUE READING
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