ABO-incompatible bone marrow transplantation: Three methods for the removal of red blood cell antibodies

@inproceedings{Tichelli1987ABOincompatibleBM,
  title={ABO-incompatible bone marrow transplantation: Three methods for the removal of red blood cell antibodies},
  author={Andr{\'e} Tichelli and Alois Gratwohl and Catherine H. Nissen and Lori A. Joseph and Andreas W{\"u}rsch and Rosemarie Wenger and B. Osterwalder and Burri Hp and Bruno Wilhelm Speck},
  year={1987}
}
We analyzed three different methods for removing red blood cell (RBC) antibodies in 28 patients before a major ABO-incompatible bone marrow transplantation (BMT). Six patients were treated with extensive plasma exchange. Antibody titers were lowered from 1:512 to 1:4 (median values). In ten patients antibodies were removed by extracorporeal immunoadsorption using an adsorbent column. Titers decreased from 1:128 to 1:32. In four of these ten patients plasma exchange was added to complete… CONTINUE READING