ABO blood group determines plasma von Willebrand factor levels: a biologic function after all?

@article{Jenkins2006ABOBG,
  title={ABO blood group determines plasma von Willebrand factor levels: a biologic function after all?},
  author={Pierre Jenkins and James S O'Donnell},
  journal={Transfusion},
  year={2006},
  volume={46 10},
  pages={1836-44}
}
For many years, an association between ABO histo-blood group and risk of thrombosis has been recognized. Blood group non-O (A, B, and AB) individuals have consistently been found to demonstrate increased incidence of both arterial and venous thrombotic disease, compared to group O individuals. This increased risk is attributable to the fact that ABO blood group influences plasma levels of a coagulation glycoprotein named von Willebrand factor (VWF). VWF levels are 25 percent higher in non-O… CONTINUE READING
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