ABO antigen and secretor statuses are not associated with gut microbiota composition in 1,500 twins

@inproceedings{Davenport2016ABOAA,
  title={ABO antigen and secretor statuses are not associated with gut microbiota composition in 1,500 twins},
  author={Emily R. Davenport and Julia K. Goodrich and Jordana T. Bell and Tim D. Spector and Ruth E. Ley and Andrew G. Clark},
  booktitle={BMC Genomics},
  year={2016}
}
Host genetics is one of several factors known to shape human gut microbiome composition, however, the physiological processes underlying the heritability are largely unknown. Inter-individual differences in host factors secreted into the gut lumen may lead to variation in microbiome composition. One such factor is the ABO antigen. This molecule is not only expressed on the surface of red blood cells, but is also secreted from mucosal surfaces in individuals containing an intact FUT2 gene… CONTINUE READING
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Genetic Determinants of the Gut Microbiome in UK Twins

  • K Goodrich Julia, R Davenport Emily, +7 authors E. Ley Ruth
  • Cell Host Microbe
  • 2016
Highly Influential
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