ABO antibody titers are not predictive of hemolytic reactions due to plasma-incompatible platelet transfusions.

@article{Karafin2012ABOAT,
  title={ABO antibody titers are not predictive of hemolytic reactions due to plasma-incompatible platelet transfusions.},
  author={Matthew S Karafin and Lorraine Blagg and Aaron A. R. Tobian and Karen E. King and Paul M. Ness and William J. Savage},
  journal={Transfusion},
  year={2012},
  volume={52 10},
  pages={2087-93}
}
BACKGROUND The overall risk of hemolytic transfusion reactions (HTRs) from plasma (minor)-incompatible platelet (PLT) transfusions and the role of a critical anti-A or anti-B titer in predicting and preventing these reactions has not been clearly established. STUDY DESIGN AND METHODS We evaluated all apheresis PLT (AP) transfusions for 3 months. Using the gel titer method, we determined the anti-A and/or the anti-B immunoglobulin (Ig)G titer for all incompatible APs. Reported febrile… CONTINUE READING