ABCB1 and ABCC1 single-nucleotide polymorphisms in patients treated with clozapine

Abstract

Clozapine (CZ) has superior efficacy to other antipsychotic agents in the treatment of schizophrenia and has been extensively used in clinical practice. ATP-binding cassette (ABC) transporter proteins are responsible for the distribution of various molecules as well as drugs across extracellular and intracellular membranes, including the blood-brain barrier… (More)
DOI: 10.2147/PGPM.S142314

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