ABC transporters involved in drug resistance in human parasites.

  title={ABC transporters involved in drug resistance in human parasites.},
  author={Philippe Leprohon and Danielle L{\'e}gar{\'e} and Marc A. Ouellette},
  journal={Essays in biochemistry},
  volume={50 1},
The ABC (ATP-binding cassette) protein superfamily is a ubiquitous and functionally versatile family of proteins that is conserved from archaea to humans. In eukaryotes, most of these proteins are implicated in the transport of a variety of molecules across cellular membranes, whereas the remaining ones are involved in biological processes unrelated to transport. The biological functions of several ABC proteins have been described in clinically important parasites and nematode worms and include… CONTINUE READING
Highly Cited
This paper has 18 citations. REVIEW CITATIONS