AB078. Knockdown of SPC25 inhibits cell proliferation and cycle progression in prostate cancer

@inproceedings{Cui2017AB078KO,
  title={AB078. Knockdown of SPC25 inhibits cell proliferation and cycle progression in prostate cancer},
  author={Feilun Cui and Jiangpeng Hu and Jian Tan and Huaming Tang},
  year={2017}
}
Prostate cancer (PCa) was one of the most commonly diagnosed malignant cancers in males in China. Cell-cycle aberration was a hallmark of cancer. SPC25, a component of Ndc80 complex, played an important role in regulating mitotic chromosome segregation. However, the functional roles of SPC25 in prostate cancer were still poorly understood. Our study showed for the first time that SPC25 was significantly upregulated in prostate cancer. To explore the molecular function roles of SPC25, we… CONTINUE READING