AB074. Why ‘Skinny-Fat’ is bad for colorectal cancer: an analysis of body composition, the perioperative human metabolome and five-year colon cancer outcomes

@inproceedings{Fleming2020AB074W,
  title={AB074. Why ‘Skinny-Fat’ is bad for colorectal cancer: an analysis of body composition, the perioperative human metabolome and five-year colon cancer outcomes},
  author={C. Fleming and Raphaela Fritsche and D. P. O’leary and Yohann Gloaguen and Jianghuai Wang and M. Corrigan and M. Mccourt and S. Killeen and E. Andrews and J. Kirwan and H. P. Redmond},
  year={2020}
}
  • C. Fleming, Raphaela Fritsche, +8 authors H. P. Redmond
  • Published 2020
  • Medicine
  • Background: High visceral adiposity (VA) and low skeletal muscle area (SMA) are poor prognostic factors in many cancers. In this study we aimed to characterise the perioperative human metabolome (combined end-product of cellular metabolism) in differential body compositions and correlate preferential metabolic pathways to five-year cancer outcomes. Methods: Patients undergoing elective resection for nonmetastatic colon cancer were prospectively enrolled. Serum samples were phlebotomised at… CONTINUE READING