AAV vectors for cardiac gene transfer: experimental tools and clinical opportunities.

@article{Pacak2011AAVVF,
  title={AAV vectors for cardiac gene transfer: experimental tools and clinical opportunities.},
  author={Christina A. Pacak and Barry Byrne},
  journal={Molecular therapy : the journal of the American Society of Gene Therapy},
  year={2011},
  volume={19 9},
  pages={1582-90}
}
Since the first demonstration of in vivo gene transfer into myocardium there have been a series of advancements that have driven the evolution of cardiac gene delivery from an experimental tool into a therapy currently at the threshold of becoming a viable clinical option. Innovative methods have been established to address practical challenges related to tissue-type specificity, choice of delivery vehicle, potency of the delivered material, and delivery route. Most importantly for therapeutic… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

Similar Papers

Loading similar papers…