AATF protects neural cells against oxidative damage induced by amyloid beta-peptide.

@article{Xie2004AATFPN,
  title={AATF protects neural cells against oxidative damage induced by amyloid beta-peptide.},
  author={Jun Xie and Qing Jun Guo},
  journal={Neurobiology of disease},
  year={2004},
  volume={16 1},
  pages={150-7}
}
Extensive loss of neurons and synapses in vulnerable regions of the brain is one of the most important pathological features of Alzheimer's disease (AD). Increased oxidative stress has been shown to contribute to the neurodegenerative process in AD. Aggregation of amyloid beta-peptide (Abeta) in amyloid plaques is one of the defining features of Alzheimer's disease. Indeed, Abeta has been shown to induce oxidative stress and apoptosis in many in vivo and in vitro models of AD. We now report… CONTINUE READING

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