AAA+ proteins: diversity in function, similarity in structure.
@article{Snider2008AAAPD, title={AAA+ proteins: diversity in function, similarity in structure.}, author={Jamie D. Snider and Walid A. Houry}, journal={Biochemical Society transactions}, year={2008}, volume={36 Pt 1}, pages={ 72-7 } }
The AAA+ (ATPases associated with various cellular activities) superfamily of proteins represents a distinct lineage of the larger class of P-loop NTPases. Members of this superfamily use the power of nucleotide binding and hydrolysis to direct molecular remodelling events. All AAA+ proteins share a common core architecture, which, through various sequence and structural modifications, has been adapted for use in a remarkably diverse range of functions. The following mini-review provides a…
147 Citations
The AAA+ superfamily of functionally diverse proteins
- BiologyGenome Biology
- 2008
SummaryThe AAA+ superfamily is a large and functionally diverse superfamily of NTPases that are characterized by a conserved nucleotide-binding and catalytic module, the AAA+ module. Members are…
AAA proteins and the life process.
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The talks that are discussed herein and the corresponding papers that follow this introduction give a good overview of the current areas of research into these proteins.
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