A5 noradrenergic neurons and the carotid sympathetic chemoreflex.

  title={A5 noradrenergic neurons and the carotid sympathetic chemoreflex.},
  author={N Koshiya and Patrice G Guyenet},
  journal={The American journal of physiology},
  volume={267 2 Pt 2},
Inhibition of neural activity in the caudal ventrolateral pons (A5 area) by microinjection of muscimol (Mus) attenuates (-65%) the carotid sympathetic chemoreflex (SChR) without altering the concomitant activation of the phrenic nerve (PND). The present study, performed in urethan-anesthetized rats, explores the possibility that activation of the noradrenergic (NE) neurons of the A5 area is involved in the SChR. The NE neuron-selective toxin 6-hydroxydopamine (6-OHDA) was microinjected… CONTINUE READING


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