A20 inactivation in ocular adnexal MALT lymphoma.

@article{Bi2012A20II,
  title={A20 inactivation in ocular adnexal MALT lymphoma.},
  author={Yingwen Bi and Naiyan Zeng and Estelle Chanudet and Yuanxue Huang and Rifat A. Hamoudi and Hongxiang Liu and Gehong Dong and Adam J Watkins and Steven C. Ley and Lifen Zou and Rongjia Chen and Xiong-zeng Zhu and Ming-Qing Du},
  journal={Haematologica},
  year={2012},
  volume={97 6},
  pages={926-30}
}
Recent studies showed A20 inactivation by deletion, mutation and promoter methylation in ocular adnexal mucosa-associated lymphoid tissue lymphoma. However, the incidences of A20 abnormalities and their clinical impact remain for the most part unknown. It is also unknown whether ABIN-1 and ABIN-2, the components of the A20 NF-κB inhibitor complex, are inactivated by genetic changes in ocular adnexal mucosa-associated lymphoid tissue lymphoma. A total of 105 cases were investigated for A20… CONTINUE READING

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MALT lymphoma: Genetic abnormalities, immunological stimulation and molecular mechanism.

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