A10 dopamine neurons: role of autoreceptors in determining firing rate and sensitivity to dopamine agonists.

@article{White1984A10DN,
  title={A10 dopamine neurons: role of autoreceptors in determining firing rate and sensitivity to dopamine agonists.},
  author={Francis J. White and Rex Wang},
  journal={Life sciences},
  year={1984},
  volume={34 12},
  pages={
          1161-70
        }
}
The present experiments investigated the relationship between the spontaneous basal firing rate of A10 dopamine (DA) neurons and their sensitivity to the rate-suppressant effects of intravenously administered apomorphine (APO) and d-amphetamine (AMP) as well as microiontophoretically ejected DA. The results indicated highly significant inverse relationships between basal neuronal activity and sensitivity to DA and DA agonists, i.e. the faster the spontaneous rate of an A10 DA neuron, the less… CONTINUE READING

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