A1 adenosine receptors modulate respiratory activity of the neonatal mouse via the cAMP-mediated signaling pathway.

Abstract

The effects of adenosine and its analogs on the function of the respiratory center were studied in the spontaneously active rhythmic slice of neonatal and juvenile mice (4-14 days old). Whole cell, spontaneous postsynaptic currents (sPSCs) and single channel KATP currents were recorded in inspiratory neurons of the pre-Bötzinger complex. Adenosine (50-600… (More)

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