A zinc-containing intraruminal device for prevention of the sporidesmin-induced cholangiopathy of facial eczema in calves.

@article{Munday2001AZI,
  title={A zinc-containing intraruminal device for prevention of the sporidesmin-induced cholangiopathy of facial eczema in calves.},
  author={Rex Munday and Angela M. Thompson and Barry L. Smith and Neale R Towers and Kate O'donnell and Rodney M McDonald and M Stirnemann},
  journal={New Zealand veterinary journal},
  year={2001},
  volume={49 1},
  pages={29-33}
}
AIM To develop and evaluate a zinc-containing intraruminal controlled-release bolus for protection of calves (175-250 kg bodyweight) against facial eczema (FE). METHODS Boluses releasing zinc, in the form of zinc oxide, at rates ranging from 1.67 to 4.25 g/day were administered to calves which were challenged 4 weeks later with the FE toxin, sporidesmin. The efficacy of the boluses in protecting against sporidesmin-induced cholangiopathy was determined by measuring serum activities of gamma… CONTINUE READING

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