A yeast gene encoding a protein homologous to the human c-has/bas proto-oncogene product

@article{Gallwitz1983AYG,
  title={A yeast gene encoding a protein homologous to the human c-has/bas proto-oncogene product},
  author={Dieter Gallwitz and Cornelia Donath and Christian Sander},
  journal={Nature},
  year={1983},
  volume={306},
  pages={704-707}
}
Organisms amenable to easy genetic analysis should prove helpful in assessing the function of at least those proto-oncogene products which are highly conserved in different eukaryotic cells. One obvious possibility is to pursue the matter in Drosophila melanogaster DNA, which has sequences homologous to several vertebrate oncogenes1–3. Another is to turn to the yeast Saccharomyces cerevisiae, if it contains proto-oncogene sequences. Here we report the identification of a gene in S. cerevisiae… CONTINUE READING
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