A yeast Golgi E-type ATPase with an unusual membrane topology.

@article{Zhong1999AYG,
  title={A yeast Golgi E-type ATPase with an unusual membrane topology.},
  author={Xiaotian Zhong and Guido Guidotti},
  journal={The Journal of biological chemistry},
  year={1999},
  volume={274 46},
  pages={32704-11}
}
E-type ATPases are involved in many biological processes such as modulation of neural cell activity, prevention of intravascular thrombosis, and protein glycosylation. In this study, we show that a gene of Saccharomyces cerevisiae, identified by similarity to that of animal ectoapyrase CD39, codes for a new member of the E-type ATPase family (Apy1p). Overexpression of Apy1p in yeast cells causes an increase in intracellular membrane-bound nucleoside di- and triphosphate hydrolase activity. The… CONTINUE READING

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