A whole-blood RNA transcript-based prognostic model in men with castration-resistant prostate cancer: a prospective study.

@article{Ross2012AWR,
  title={A whole-blood RNA transcript-based prognostic model in men with castration-resistant prostate cancer: a prospective study.},
  author={Robert W. Ross and Matthew David Galsky and Howard I. Scher and Jay Magidson and Karl Wassmann and Gwo-Shu Lee and Leah Minnie Katz and Sumit K. Subudhi and Aseem Anand and M. Fleisher and Philip W. Kantoff and William K Oh},
  journal={The Lancet. Oncology},
  year={2012},
  volume={13 11},
  pages={1105-13}
}
BACKGROUND Survival for patients with castration-resistant prostate cancer is highly variable. We assessed the effectiveness of a whole-blood RNA transcript-based model as a prognostic biomarker in castration-resistant prostate cancer. METHODS Peripheral blood was prospectively collected from 62 men with castration-resistant prostate cancer on various treatment regimens who were enrolled in a training set at the Dana-Farber Cancer Institute (Boston, MA, USA) from August, 2006, to June, 2008… CONTINUE READING
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