A white-specific gene in the white-opaque switching system of Candida albicans.

@article{Srikantha1993AWG,
  title={A white-specific gene in the white-opaque switching system of Candida albicans.},
  author={Thyagarajan Srikantha and David R Soll},
  journal={Gene},
  year={1993},
  volume={131 1},
  pages={53-60}
}
The Candida albicans strain WO-1 cells switch spontaneously, frequently, and reversibly between white and opaque colony-forming units which differ dramatically in their budding phenotypes. By screening a subtracted white cDNA library, the first white-specific cDNA, cWh11, was isolated and sequenced. This, in turn, was used to clone the Wh11 gene. Wh11 shows significant homology to the glucose/lipid-regulated GLP1 gene of Saccharomyces cerevisiae. Upon temperature-induced mass conversion from… CONTINUE READING

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