A web application for sample size and power calculation in case-control microbiome studies

@article{Mattiello2016AWA,
  title={A web application for sample size and power calculation in case-control microbiome studies},
  author={Federico Mattiello and Bie M. P. Verbist and Karoline Faust and Jeroen Raes and William D. Shannon and Luc Bijnens and Olivier Thas},
  journal={Bioinformatics},
  year={2016},
  volume={32 13},
  pages={2038-40}
}
UNLABELLED : When designing a case-control study to investigate differences in microbial composition, it is fundamental to assess the sample sizes needed to detect an hypothesized difference with sufficient statistical power. Our application includes power calculation for (i) a recoded version of the two-sample generalized Wald test of the 'HMP' R-package for comparing community composition, and (ii) the Wilcoxon-Mann-Whitney test for comparing operational taxonomic unit-specific abundances… CONTINUE READING
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