A voxel-based morphometric study to determine individual differences in gray matter density associated with age and cognitive change over time.

@article{Tisserand2004AVM,
  title={A voxel-based morphometric study to determine individual differences in gray matter density associated with age and cognitive change over time.},
  author={Danielle J Tisserand and Martin P. J. van Boxtel and Jens C. Pruessner and P. Hofman and Alan C. Evans and Jelle Jolles},
  journal={Cerebral cortex},
  year={2004},
  volume={14 9},
  pages={966-73}
}
Voxel-based morphometry (VBM) was used to examine the relation between age and gray matter density cross-sectionally and to study the association between gray matter density and longitudinal decline in performance on cognitive tests in healthy, non-demented elderly individuals. Participants were neuropsychologically tested at baseline and again after 3 years. Thirty-seven subjects (mean age 72.5 years) who showed a decline in cognitive test performance at follow-up were compared with 38… CONTINUE READING
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