A virally induced obesity syndrome in mice.

  title={A virally induced obesity syndrome in mice.},
  author={Michael J Lyons and I M Faust and R B Hemmes and Daniel R. Buskirk and Jules Hirsch and John B. Zabriskie},
  volume={216 4541},
An obesity syndrome was found in a number of mice infected as young adults with canine distemper virus, a morbillivirus antigenically related to measles. Body weights of obese animals 16 to 20 weeks after infection were comparable to those reported for genetically obese mice and for mice rendered obese by hypothalamic lesions. The total number of adipocytes in specific fat deposits was greater in obese animals than in their lean littermates. This hyperplasia was accompanied by moderate cell… CONTINUE READING


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