A viral transcription factor exhibits antiviral RNA silencing suppression activity independent of its nuclear localization.

@article{Lukhovitskaya2014AVT,
  title={A viral transcription factor exhibits antiviral RNA silencing suppression activity independent of its nuclear localization.},
  author={Nina I. Lukhovitskaya and Ramesh R Vetukuri and Indu Sama and Srinivas Thaduri and Andrey G. Solovyev and Eugene I Savenkov},
  journal={The Journal of general virology},
  year={2014},
  volume={95 Pt 12},
  pages={2831-7}
}
Viral suppressors of RNA silencing (VSRs) are critical for the success of virus infection and efficient accumulation of virus progeny. The chrysanthemum virus B p12 protein acts as a transcription factor to regulate cell size and proliferation favourable for virus infection. Here, we showed that the p12 protein suppressed RNA silencing and was able to complement a VSR-deficient unrelated virus. Moreover, p12 counter-silencing activity could be uncoupled from its function as a transcription… CONTINUE READING

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