A viral gene confers hypovirulence-associated traits to the chestnut blight fungus.

@article{Choi1992AVG,
  title={A viral gene confers hypovirulence-associated traits to the chestnut blight fungus.},
  author={Jae Gil Choi and Donald L. Nuss},
  journal={The EMBO journal},
  year={1992},
  volume={11 2},
  pages={
          473-7
        }
}
A viral double-stranded (ds)RNA associated with reduced virulence (hypovirulence) and the accompanying biological control of the chestnut blight fungus, Cryphonectria parasitica, was shown recently to contain two contiguous coding domains designated ORF A and ORF B. We report here that transformation of an isogenic virulent, dsRNA-free C. parasitica strain with a cDNA copy of ORF A conferred traits similar to those exhibited by the dsRNA-containing hypovirulent strain: characteristics included… CONTINUE READING
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