A view through the clouds of imprinting.

  title={A view through the clouds of imprinting.},
  author={Jason L. Burns and Dean A Jackson and Andrew Bassim Hassan},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  volume={15 10},
The purpose of this review is to examine whether our current knowledge of the higher order control of gene expression and nuclear organization can help us understand the mechanisms of genomic imprinting. Imprinting involves the inheritance of a silenced allele of a gene through either a paternal or maternal germline. We have approached the problem of imprinting using a model based on the dynamic attachment of chromatin loops to immobilized RNA polymerases and control elements. We have combined… CONTINUE READING

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