A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18.

@article{Prasse2006AVC,
  title={A vicious circle of alveolar macrophages and fibroblasts perpetuates pulmonary fibrosis via CCL18.},
  author={Antje Prasse and Dmitri V. Pechkovsky and Galen B. Toews and Wolfgang Jungraithmayr and Florian Kollert and Torsten Goldmann and Ekkehard Vollmer and Joachim Mueller-Quernheim and Gernot Zissel},
  journal={American journal of respiratory and critical care medicine},
  year={2006},
  volume={173 7},
  pages={781-92}
}
RATIONALE Recently, models of macrophage activation have been revised. Macrophages stimulated with Th2 cytokines have been classified as alternatively activated. OBJECTIVES This article examines the expression and regulation of CC chemokine ligand 18 (CCL18), a marker of alternative activation, by human alveolar macrophages (AMs). METHODS AM were obtained from bronchoalveolar lavage (BAL) fluid of patients with idiopathic pulmonary fibrosis, sarcoidosis, or hypersensitivity pneumonitis (n… CONTINUE READING

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CCL18 expression and production by human alveolar macrophages in co-culture with lung fibroblasts [abstract

  • DV Pechkovsky, A Prasse, C Ludwig, H Goebel, J Mueller-Quernheim, G. Zissel
  • Presented at the International Colloquium on Lung…
  • 2004
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