A versatile catalyst for Heck reactions of aryl chlorides and aryl bromides under mild conditions.

@article{Littke2001AVC,
  title={A versatile catalyst for Heck reactions of aryl chlorides and aryl bromides under mild conditions.},
  author={Adam F. Littke and Gregory C Fu},
  journal={Journal of the American Chemical Society},
  year={2001},
  volume={123 29},
  pages={6989-7000}
}
In the presence of Cy2NMe, Pd/P(t-Bu)3 serves as an exceptionally mild and versatile catalyst for Heck reactions of aryl chlorides and bromides. A sterically and electronically diverse array of aryl bromides, as well as activated aryl chlorides, couple with a range of mono- and disubstituted olefins at room temperature, furnishing the arylated product with… CONTINUE READING