A versatile, quantitative analytical method for pharmaceutical relevant lipids in drug delivery systems.

@article{Jeschek2016AVQ,
  title={A versatile, quantitative analytical method for pharmaceutical relevant lipids in drug delivery systems.},
  author={Dominik Jeschek and Gabriele Lhota and Jakob Wallner and Karola Vorauer-Uhl},
  journal={Journal of pharmaceutical and biomedical analysis},
  year={2016},
  volume={119},
  pages={
          37-44
        }
}
Over the past few years, liposomal formulations as drug carrier systems have markedly advanced in pharmaceutical research and development. Therefore, analytical methods to characterize liposome-based formulations are required. One particular issue in liposome analysis is the imbalance of lipid ratios within the vesicle formulations and the detectability of degradation products such as lysophospholipids and fatty acids caused by hydrolysis, especially in low molar ranges. Here, a highly… CONTINUE READING
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