A venlafaxine and mirtazapine-induced serotonin syndrome confirmed by de- and re-challenge

  title={A venlafaxine and mirtazapine-induced serotonin syndrome confirmed by de- and re-challenge},
  author={Liesbeth Decoutere and Sabrina de Winter and Liesbeth Vander Weyden and Isabel Spriet and Maarten Schrooten and Jos Tournoy and Katleen Fagard},
  journal={International Journal of Clinical Pharmacy},
Case description A 85 year old woman with a history of severe depression treated with mirtazapine and venlafaxine was admitted to the hospital twice after progressive deterioration of her general condition evolving to unconsciousness. Clinicians diagnosed a metabolic encephalopathy caused by a urinary tract infection which was treated appropriately. Although mirtazapine was stopped during the first hospitalization, the patient’s general practitioner restarted mirtazapine four days before… Expand
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  • 1998
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