A vector projection approach to predicting HIV protease cleavage sites in proteins.

Abstract

A vector projection method is proposed to predict the cleavability of oligopeptides by extended-specificity site proteases. For an enzyme with eight specificity subsites the substrate octapeptide can be uniquely expressed as a vector in an 8-dimensional space, whose eight bases correspond to the amino acids at the eight subsites, P4, P3, P2, P1, P1', P2… (More)

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Cite this paper

@article{Chou1993AVP, title={A vector projection approach to predicting HIV protease cleavage sites in proteins.}, author={Kuo-Chen Chou and Chun-Ting Zhang and Ferenc J. Kezdy}, journal={Proteins}, year={1993}, volume={16 2}, pages={195-204} }