A variant of the transcription factor 7-like 2 (TCF7L2) gene and the risk of posttransplantation diabetes mellitus in renal allograft recipients.

@article{Kang2008AVO,
  title={A variant of the transcription factor 7-like 2 (TCF7L2) gene and the risk of posttransplantation diabetes mellitus in renal allograft recipients.},
  author={Eun Seok Kang and Myoung Soo Kim and Yu Seun Kim and Kyu Yeon Hur and Seung Jin Han and Chung Mo Nam and Chul Woo Ahn and Bong Soo Cha and Soon Il Kim and Hyun Chul Lee},
  journal={Diabetes care},
  year={2008},
  volume={31 1},
  pages={63-8}
}
OBJECTIVE Posttransplantation diabetes mellitus (PTDM) is a major complication associated with kidney transplantation. Defects in insulin secretion play a pivotal role in the pathogenesis of PTDM. A polymorphism in the transcription factor 7-like 2 (TCF7L2) gene was reported to be associated with type 2 diabetes and possibly associated with an insulin secretion defect. The aim of this study was to investigate the association between genetic variations in TCF7L2 and PTDM in renal allograft… CONTINUE READING

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New-onset diabetes mellitus after renal transplantation.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia • 2016

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