A variant of estrogen receptor-, hER-36 : Transduction of estrogen-and antiestrogen-dependent membrane-initiated mitogenic signaling

@inproceedings{Wang2006AVO,
  title={A variant of estrogen receptor-, hER-36 : Transduction of estrogen-and antiestrogen-dependent membrane-initiated mitogenic signaling},
  author={Zhaoyi Wang and Xintian Zhang and Peng Shen and Brian W. Loggie and Yunchao Chang and Thomas F. Deuel},
  year={2006}
}
The status of the 66-kDa human estrogen receptor(hER66) is a critical determinant in the assessment of the prognosis and in the design of treatment strategies of human breast cancer. Recently, we cloned the cDNA of an alternatively spliced variant of hER66, termed hER36; the predicted protein lacks both transcriptional activation domains of hER66 but retains its DNA-binding domain, partial dimerization, and ligand-binding domains and three potential myristoylation sites located near the N… CONTINUE READING

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