A variant in microRNA-196a2 is associated with susceptibility to hepatocellular carcinoma in Chinese patients with cirrhosis.

@article{Li2010AVI,
  title={A variant in microRNA-196a2 is associated with susceptibility to hepatocellular carcinoma in Chinese patients with cirrhosis.},
  author={Xiao-Dong Li and Zhi-gao Li and Xian-Xu Song and Chun-Fu Liu},
  journal={Pathology},
  year={2010},
  volume={42 7},
  pages={669-73}
}
AIMS Cirrhosis is an important risk factor for hepatocellular carcinoma (HCC) in China, while little is known of the genetic susceptibility to hepatocarcinogenesis. Traditional approaches to identification of novel genetic predisposition genes have focused on protein encoding genes. There is evidence to suggest that microRNAs (miRNA) may play an important role in tumorigenesis. Recent studies have implicated that the rs11614913 SNP in miR-196a2 may be associated with susceptibility to lung… CONTINUE READING