A variant form of neuronal ceroid lipofuscinosis in American bulldogs.

@article{Evans2005AVF,
  title={A variant form of neuronal ceroid lipofuscinosis in American bulldogs.},
  author={Jason Evans and Martin L. Katz and Donald Levesque and Gloria Diane Shelton and Alexander de Lahunta and Dennis W. O'Brien},
  journal={Journal of veterinary internal medicine},
  year={2005},
  volume={19 1},
  pages={44-51}
}
Neuronal ceroid lipofuscinoses (NCLs) are inherited neurodegenerative diseases characterized by accumulations of autofluorescent lipopigments within cells of the nervous system. Nine related American Bulldogs demonstrated dysmetria in all limbs and paraparesis. Nonambulatory tetraparesis was observed only in the later stages of the disease. The clinical signs developed between 1 and 3 years of age and were slowly progressive over several years, which is inconsistent with most reports in other… CONTINUE READING

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