A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1.

@article{Jeon1995AVE,
  title={A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1.},
  author={Ik Soo Jeon and Jeniffer N Davis and Ben Braun and Jack E Sublett and Martine F Roussel and Christopher T. Denny and David N. Shapiro},
  journal={Oncogene},
  year={1995},
  volume={10 6},
  pages={1229-34}
}
Most Ewing's sarcomas or related primitive neuroectodermal tumors have the (11;22)(q24;q12) or less frequently the (21;22)(q22;q12) translocation. These rearrangements fuse the EWS gene on chromosome 22q12 to either the FLI1 or ERG genes, both members of the ETS family of transcription factors. Simple variant chromosomal translocations have been occasionally described in these tumors. We have identified a third Ewing's sarcoma translocation, the t(7;22)(p22;q12), that fuses EWS to the human… CONTINUE READING
122 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 122 extracted citations

Similar Papers

Loading similar papers…