A validation study of the WHO analgesic ladder: a two-step vs three-step strategy

  title={A validation study of the WHO analgesic ladder: a two-step vs three-step strategy},
  author={Marco Maltoni and Emanuela Scarpi and Caterina Modonesi and Alessandro Passardi and Sebastiano Calpona and Adriana Turriziani and Raffaella Speranza and Davide Tassinari and Pierantonio Magnani and Denis Saccani and Luigi Montanari and Britt Roudnas and Dino Amadori},
  journal={Supportive Care in Cancer},
The aims of the present study were to verify whether an innovative therapeutic strategy for the treatment of mild-moderate chronic cancer pain, passing directly from step I to step III of the WHO analgesic ladder, is more effective than the traditional three-step strategy and to evaluate the tolerability and therapeutic index in both strategies. Patients aged 18 years or older with multiple viscera or bone metastases or with locally advanced disease were randomized. Pain intensity was assessed… CONTINUE READING


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WHO analgesic ladder-or lift

  • J Porta-Sales, X Gòmez-Batiste, A TucaRodriguez, F Madrid-Juan, J EspinosaRojas, J Trelis-Navarro
  • Eur J Palliat Care
  • 2003
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