A validation of the most commonly used protocol to predict the success of single-dose methotrexate in the treatment of ectopic pregnancy.

@article{Kirk2007AVO,
  title={A validation of the most commonly used protocol to predict the success of single-dose methotrexate in the treatment of ectopic pregnancy.},
  author={Emma Kirk and George Condous and Ben Van Calster and Zara Haider and Sabine Van Huffel and Dirk Timmerman and Tom Bourne},
  journal={Human reproduction},
  year={2007},
  volume={22 3},
  pages={858-63}
}
BACKGROUND Currently, the likely success of single-dose methotrexate (MTX) (50 mg/m(2)) for the treatment of ectopic pregnancy is indicated by a >15% decrease in hCG from days 4-7 after administration. The aim of this study was to assess this protocol and to develop new rules that could be used to predict the outcome at an earlier stage. METHODS Data were collected prospectively. Women receiving MTX for an ectopic pregnancy had serum hCG and progesterone levels checked on days 1, 3, 4, 5 and… CONTINUE READING

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ß-hCG and prediction of therapeutic success in ectopic pregnancies treated with methotrexate, results from a prospective observational study.

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How feasible is expectant management of interstitial ectopic pregnancy?

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References

Publications referenced by this paper.
Showing 1-10 of 15 references

Single-dose methotrexate: an expanded clinical trial.

American journal of obstetrics and gynecology • 1993
View 7 Excerpts
Highly Influenced

Single-dose methotrexate for treatment of ectopic pregnancy.

Obstetrics and gynecology • 1991
View 3 Excerpts
Highly Influenced

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